INSIGHTS ON PHARMACEUTICAL INSPECTION

PHARMACEUTICAL INSPECTION SOLUTIONS

  • Integrity testing of foil pouches offers a unique set of challenges. In most packaging processes that involve foil as the product barrier there is a concern about the incidence of punctures in the foil. These defects (typically called micro-voids) can be created as the foil is being rolled in thin sheets and tiny particles are inadvertently rolled into the foil. The most common defect is caused from the handling of the packages during the assembly of the foil and insertion of the drug product.

  • The HDV-AT6 provides high voltage leak detection for glass vials sizes.

  • METTLER TOLEDO Safeline pharmaceutical metal detector systems are designed to offer maximum flexibility in process areas. A compact footprint enables systems to be inserted into areas where space is restricted. Robust, low profile, fully rotating castors provide ease of mobility, enabling the system to be used in multiple locations. Flexibility is further enhanced by the ability of the metal detection head to be adjusted easily (without the need for tools) in all three axes to suit any configuration.

  • The VeriPac 410 inspection system uses force decay technology for non-destructive seal and leak detection for blister packs, sachets, and pouches with low headspace.

  • A helium based test method for verifying the integrity of a blister card holding drug product has been proven to be the most effective approach due to the extreme sensitivity offered. The test method relies on detecting helium sealed in the package system as it escapes through micro-channels in the package. A test sequence begins by placing the package in the test fixture and a vacuum is quickly drawn. The resulting pressure differential causes helium to escape through potential holes or cracks in the package.