Contract Manufacturing Featured Articles

1. What Pharmacies Often Miss In USP <800> Compliance 5/27/2026

   Master USP <800> compliance by transitioning from standalone equipment to an integrated system design. Review key protocols for a multi-layered strategy to mitigate cumulative drug risks.

2. How Tech Can Drive In-House API Manufacturing 5/20/2026

   Pharmaceutical companies are increasingly moving API production in-house, taking advantage of advanced manufacturing technologies (AMTs) like continuous flow chemistry and automation to drive efficiency, though high costs and cultural shifts remain challenges. By investing in specialized training and strategic facility upgrades, manufacturers can leverage these tools to mitigate supply chain risks, enhance quality, reduce operational complexity, and gain greater control over production timelines.

3. Highly Potent Active Pharmaceutical Ingredients 5/19/2026

   Empower safer, faster development of complex therapeutics by partnering with an HPAPI‑focused CDMO that delivers proven containment, rigorous quality, and end‑to‑end expertis

4. LYO Cycle Development Ensures Success For Oncology Drug Scale-Up 5/14/2026

   An optimized lyophilization cycle removes excess moisture during scale‑up by adjusting drying for larger equipment, improving stability, maintaining efficiency, and supporting clinical validation.

5. Accelerating ADC Analytical Method Development Through Platform Innovation 5/11/2026

   Leverage a platform-based analytical development strategy to accelerate ADC IND readiness through early CQA identification, reduced development risk, and streamlined progression from development to patients.

6. From 51% Yield To 87% With Targeted Impurity Removal 5/7/2026

   Targeted impurity identification and purification redesign dramatically improved yield, reduced process complexity, and enabled reliable API supply for Phase II clinical development.

7. Overcoming Product Instability And Improving Yield 5/7/2026

   Early identification of hidden product instability enabled rapid process adjustments, improving yield and keeping a preclinical toxicology program on track despite challenging reaction conditions.

8. Producing Quality APIs At Scale 5/7/2026

   Targeted process optimization transformed an early‑phase API with yield and impurity challenges into a scalable, high‑quality manufacturing process ready to support ongoing drug development.

9. The TIDES Manufacturing Mandate: Why Incrementalism Fails And Integration Prevail 5/7/2026

   Manufacturing strategies for peptides and oligonucleotides are being reshaped by scale, complexity, and chronic use. An integrated, end‑to‑end approach shows how early design decisions can prevent costly bottlenecks later.

10. Advancing Nanomedicine Production With Flow Manufacturing 5/6/2026

    Learn how flow manufacturing enables scalable, reproducible nanomedicine production with tighter control, consistent particle quality, and smooth lab-to-commercial scale‑up.